Brodifaccoum is indirect anticoagulant. It is a kindo of rodenticide effective against
warfarin-resistant rats. It is usually sold as ready to use bait in pellets, mini-pellets
and waterproof bait containing 0.005% brodifacoum (loose or in bait packs).Indicated
for control of Norwegian rats, roof rats and house mice in public, industrial and
commercial buildings, in residences and outdoor urban areas. The application may
be carried out by professional pest control personnel orby the public in general.
Theoretically, the substance may be considered for development as a therapeutic
agent in anticoagulant therapy, but the difficulty in reversal of effects constitutes a
major disadvantage (Jones et al., 1984).
Product name: Brodifacoum 97%Tech
Pesticide category: Rodenticide
Appearance (TC): White powder
Brand name: Greenriver/ as per customers request.
Controls most rodent pests, including Rattus norvegicus, R. rattus, Mus musculus
and M. domesticus, at lower rates than many other anticoagulants (e.g. warfarin
and pindone); also Cricetus cricetus, Mesocricetus auratus, Microtus pennsylvanicus,
M. pinetorum, R. argentiventer, R. rattus mindanensis and rodents, such as hamsters,
that are difficult to control with other anticoagulants. Potency is such that a rodent may
absorb a lethal dose by taking a 50 mg/kg bait as part of its food intake on only one occasion.
For a review, see A. P. Buckle & R. H. Smith, "Rodent Pests and their Control", CABI (1994).
Form White powder; (tech., off-white to buff or beige powder). M.p. 228-232 °C (tech.)
V.p. <<0.001 mPa (20 °C, gas saturation method)
S.g./density 1.42 (25 °C, tech.)
Solubility In water 3.8 ?10-3 (pH 5.2), 0.24 (pH 7.4), 10 (pH 9.3) (all in mg/l, 20 °C). In acetone 20, chloroform 3, benzene <6 (all in mg/l, 20 °C).
Stability Thermally (up to 50 °C) and photolytically (30 d in direct sunlight) stable. Degraded by u.v. light when in solution. pKa A very weak acid which is too lipophilic to form water-soluble salts.
Mode of Action:
Oral Acute oral LD50 for male rats 0.4, male rabbits 0.2, male mice 0.4, female guinea pigs 2.8, cats c. 25, dogs 0.25-3.6 mg/kg. Skin and eye Acute percutaneous LD50 for rabbits 0.25-0.63 mg/kg. Slight to mild skin and eye irritant (rabbits). A moderate skin sensitiser (guinea pigs), but negligible risk of sensitisation from formulated product.
Inhalation LC50 (4 h) for male rats 4.86, female rats 3.95 mg/l air.
Product name:Brodifacoum 97%Tech
Content of a.i. (IPA)
The ratio of isomers (A/B)
Insolubles in acetone, %
Loss on drying, %
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